Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 5/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236029 | 0.87 | GPR119 (0.44) | NSD2ALKCTSLCTSBCTSS | |
| SCHEMBL6234182 | 0.86 | MAPT (0.53) | GBA1ALKACHEEGFR | |
| SCHEMBL6239744 | 0.82 | GBA1 (0.63) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6238044 | 0.81 | GBA1 (0.62) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6239397 | 0.81 | GBA1 (0.62) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6238470 | 0.80 | CTSS (0.68) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6237209 | 0.80 | CTSK (0.67) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6238645 | 0.79 | GBA1 (0.51) | GBA1CTSLCTSBCTSSCTSK | |
| SCHEMBL6272121 | 0.77 | GBA1 (0.50) | NSD2GBA1ALKCTSLCTSB | |
| SCHEMBL6242579 | 0.77 | GBA1 (0.50) | GBA1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |