Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239608 | 0.87 | NSD2 (0.47) | ACHENSD2CTSLCTSBCTSS | |
| SCHEMBL6237944 | 0.82 | CTSK (0.49) | CTSLCTSBCTSSCTSKMAPT | |
| SCHEMBL6236367 | 0.81 | CTSK (0.63) | CTSLCTSBCTSSCTSKPOLB | |
| SCHEMBL8314339 | 0.81 | CTSS (0.63) | CTSLCTSBCTSSCTSKPOLB | |
| SCHEMBL20919401 | 0.74 | POLB (0.56) | GPR119ACHEPOLBMAPT | |
| SCHEMBL6236127 | 0.73 | CTSL (0.60) | GPR119NSD2CTSLCTSBCTSS | |
| SCHEMBL6234182 | 0.73 | MAPT (0.53) | ACHEALKMAPT | |
| SCHEMBL30062832 | 0.72 | GPR119 (0.51) | GPR119POLBGPR6 | |
| SCHEMBL22711990 | 0.72 | GPR6 (0.73) | GPR6 | |
| SCHEMBL27226676 | 0.72 | GPR119 (0.54) | GPR119ACHENSD2MAPTPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |