Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242558 | 0.84 | KDM4E (0.53) | MAPTLMNAKDM4EATMSMN1; SMN2 | |
| SCHEMBL6244798 | 0.79 | CYP2D6 (0.55) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6243775 | 0.78 | KDM4E (0.43) | MAPTLMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6240374 | 0.78 | MAPT (0.46) | MAPTLMNAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6244316 | 0.77 | HTT (0.53) | MAPTLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL4004039 | 0.76 | KDM4E (0.53) | MAPTLMNAKDM4EATMSMN1; SMN2 | |
| SCHEMBL27634733 | 0.69 | ATM (0.66) | MAPTLMNAKDM4EATMSMN1; SMN2 | |
| SCHEMBL4006631 | 0.69 | KDM4E (0.55) | MAPTLMNAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7247599 | 0.69 | KMT2A (0.52) | MAPTLMNAKDM4EATMSMN1; SMN2 | |
| SCHEMBL6242433 | 0.67 | HTR1A (0.41) | MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |