Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240789 | 0.84 | MAPT (0.48) | KDM4ELMNAMAPTALDH1A1KMT2A | |
| SCHEMBL6243775 | 0.84 | KDM4E (0.43) | KDM4ELMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6240374 | 0.77 | MAPT (0.46) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL4009635 | 0.76 | DRD4 (0.61) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL6244798 | 0.74 | CYP2D6 (0.55) | MAPTALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6244316 | 0.74 | HTT (0.53) | KDM4ELMNAMAPTALDH1A1KMT2A | |
| SCHEMBL6242433 | 0.69 | HTR1A (0.41) | KDM4ELMNAMAPTALDH1A1DRD4 | |
| SCHEMBL7806812 | 0.66 | RAB9A (0.74) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL4007220 | 0.66 | DRD4 (0.62) | KDM4ELMNAMAPTALDH1A1DRD4 | |
| SCHEMBL4006631 | 0.66 | KDM4E (0.55) | KDM4ELMNAMAPTALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |