Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141361 | 0.82 | GCK (0.45) | GCKLNPEP | |
| SCHEMBL623515 | 0.81 | GCK (0.61) | GCK | |
| SCHEMBL624577 | 0.73 | GCK (0.49) | GCKLNPEP | |
| SCHEMBL624697 | 0.72 | GCK (0.50) | GCKLNPEP | |
| SCHEMBL21881827 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL184640 | 0.70 | GCK (0.50) | GCK | |
| SCHEMBL184731 | 0.69 | GCK (0.50) | GCK | |
| SCHEMBL184906 | 0.69 | MMP13 (0.51) | GCK | |
| SCHEMBL622830 | 0.69 | GCK (0.55) | GCK | |
| SCHEMBL184712 | 0.68 | GCK (0.62) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |