SCHEMBL624588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL624608	0.89	KDM4E (0.47)	TRPV3SLC6A3SLC6A4SLC6A2KDM4E
	SCHEMBL625378	0.87	TRPV3 (0.49)	TRPV3SLC6A3HSD11B1SLC6A4SLC6A2
	SCHEMBL625714	0.86	SLC6A4 (0.43)	TRPV3SLC6A3SLC6A4SLC6A2KDM4E
	SCHEMBL625411	0.86	SLC6A3 (0.44)	TRPV3SLC6A3SLC6A4SLC6A2KDM4E
	SCHEMBL28804184	0.84	HSD11B1 (0.43)	TRPV3SLC6A3HSD11B1SLC6A4SLC6A2
	SCHEMBL626047	0.83	NR1I2 (0.56)	TRPV3SLC6A3SLC6A4SLC6A2NR1I2
	SCHEMBL28804188	0.82	SLC6A3 (0.38)	TRPV3SLC6A3HSD11B1SLC6A4SLC6A2
	SCHEMBL625340	0.81	TRPV3 (0.65)	TRPV3SLC6A3SLC6A4SLC6A2
	SCHEMBL626127	0.79	TRPV3 (0.46)	TRPV3SLC6A3SLC6A4SLC6A2KDM4E
	SCHEMBL627064	0.78	SLC6A4 (0.49)	TRPV3SLC6A3SLC6A4SLC6A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.