Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 9/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247880 | 0.86 | RECQL (0.43) | RECQL | |
| SCHEMBL6246748 | 0.83 | GRK2 (0.40) | RORCRXFP1VNN1RECQLCYP2C9 | |
| SCHEMBL6248753 | 0.83 | EPHX1 (0.37) | RECQL | |
| SCHEMBL6246114 | 0.82 | ALDH1A1 (0.48) | — | |
| SCHEMBL6265380 | 0.80 | LMNA (0.41) | — | |
| SCHEMBL6248097 | 0.78 | PTGS1 (0.44) | RXFP1RECQLCYP3A4 | |
| SCHEMBL6246207 | 0.78 | LMNA (0.34) | RECQL | |
| SCHEMBL6244821 | 0.77 | NQO2 (0.46) | RORCRXFP1CYP2C9CYP3A4 | |
| SCHEMBL6248564 | 0.76 | MAPT (0.43) | RORCRXFP1RECQL | |
| SCHEMBL6247079 | 0.76 | JAK2 (0.38) | RORCRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037196-A2 | SUBSTITUTED 2-ARYLMETHYLENE-N-ARYL-N'-ARYL-MALONAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA, INC. (US) | 2005-04-28 | — | — | WO | claimed |