Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625589 | 0.81 | MAPK1 (0.45) | MAPTSMN1; SMN2RAB9AHTTMAOB | |
| SCHEMBL28575414 | 0.81 | ALDH1A1 (0.56) | MAPTHTTMAOBALDH1A1KMT2A | |
| SCHEMBL28575415 | 0.81 | ALDH1A1 (0.56) | MAPTHTTMAOBALDH1A1KMT2A | |
| SCHEMBL625784 | 0.72 | KMT2A (0.57) | RAB9AMAOBALDH1A1KMT2AMEN1 | |
| SCHEMBL624231 | 0.72 | MAPK1 (0.45) | MAPTSMN1; SMN2RAB9AHTTATM | |
| SCHEMBL28571361 | 0.72 | MAPT (0.54) | MAPTSMN1; SMN2RAB9AHTTATM | |
| SCHEMBL28587113 | 0.70 | EGFR (0.50) | MAPTRAB9AATMMAOBALDH1A1 | |
| SCHEMBL28587111 | 0.70 | EGFR (0.50) | MAPTRAB9AATMMAOBALDH1A1 | |
| SCHEMBL625559 | 0.70 | MAOB (0.42) | MAPTSMN1; SMN2RAB9AHTTMAOB | |
| SCHEMBL30852828 | 0.69 | MAPT (1.00) | MAPTSMN1; SMN2RAB9AHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |