Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575414 | 0.77 | ALDH1A1 (0.56) | MAOBKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL28575415 | 0.77 | ALDH1A1 (0.56) | MAOBKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL625589 | 0.74 | MAPK1 (0.45) | MAOBKDM4EHTTMAPTNPC1 | |
| SCHEMBL625784 | 0.74 | KMT2A (0.57) | MAOBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL27850501 | 0.71 | KMT2A (0.40) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL625104 | 0.71 | DYRK1A (0.60) | MAOBHTTMAPTNPC1RAB9A | |
| SCHEMBL625103 | 0.71 | DYRK1A (0.60) | MAOBHTTMAPTNPC1RAB9A | |
| SCHEMBL624667 | 0.70 | MAPT (0.53) | MAOBKDM4EHTTMAPTNPC1 | |
| SCHEMBL28587113 | 0.67 | EGFR (0.50) | MAOBMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL28587111 | 0.67 | EGFR (0.50) | MAOBMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |