Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10371670 | 0.86 | MAPT (0.47) | MAPTTDP1L3MBTL1MAPK1CDK1 | |
| SCHEMBL10372977 | 0.85 | L3MBTL1 (0.53) | MAPTTDP1L3MBTL1MAPK1ATP4A | |
| SCHEMBL6876891 | 0.84 | ALDH1A1 (0.51) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9688517 | 0.81 | AGXT (0.46) | MAPTATP4AATP4BADRA1DADRA1A | |
| SCHEMBL10917428 | 0.79 | MAPT (0.57) | MAPTTDP1L3MBTL1MAPK1ATP4A | |
| SCHEMBL18233757 | 0.78 | PTPN1 (0.48) | MAPTTDP1L3MBTL1MAPK1ATP4A | |
| SCHEMBL4684239 | 0.78 | MGAM (0.44) | MAPTTDP1L3MBTL1MAPK1ATP4A | |
| SCHEMBL28749497 | 0.75 | AOC3 (0.52) | MAPTTDP1L3MBTL1MAPK1AOC3 | |
| SCHEMBL28108814 | 0.75 | ABCB1 (0.50) | MAPTTDP1L3MBTL1MAPK1MGAM | |
| SCHEMBL27578473 | 0.75 | AOC3 (0.49) | MAPTTDP1L3MBTL1MAPK1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040158066-A1 | Novel pyridylmethylaminopyrimidines | ALTANA PHARMA AG (DE) | 2004-08-12 | — | — | US | disclosed |
| EP-1395592-A1 | NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES | ALTANA Pharma AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094831-A1 | NOVEL PYRIDYLMETHYLAMINOPYRIMIDINES | ALTANA PHARMA AG (DE) | 2002-11-28 | — | — | WO | disclosed |
| EP-0390842-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-10-10 | — | — | EP | disclosed |
| WO-1989005299-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158066-A1 | Novel pyridylmethylaminopyrimidines | PGLS, PLPBP, PDXK | MAPT 4312/4885TDP1 2704/4885L3MBTL1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.