SCHEMBL624749

SCHEMBL624749

CCCCOC(=O)C(C)N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
ATM Q13315 1/20 0.50
TSHR P16473 5/20 0.47
HPGD P15428 2/20 0.47
HCAR2 Q8TDS4 1/20 0.44
NAAA Q02083 1/20 0.43
LMNA P02545 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
PDE4D Q08499 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPSR1 Q6W5P4 3/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 2/20 0.42
SLC15A1 P46059 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181783 1.00 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL213810 1.00 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL4380145 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL213809 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL4731637 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL18378673 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL4672442 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL253585 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL2382560 0.92 ALDH1A1 (0.47) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL23510790 0.91 NAAA (0.50) ALDH1A1ATMTSHRHCAR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644577-B Environment-friendly preparation method of substituted isonitrile compound 新发药业有限公司 2023-06-27 CN claimed
CN-109836374-B Environment-friendly preparation method of vitamin B6 新发药业有限公司 2020-10-30 CN claimed
CN-109836373-B Environment-friendly preparation method of vitamin B6 and tail gas recycling method 新发药业有限公司 2020-10-02 CN claimed
CN-109836373-A A kind of environmentally friendly method prepared and circulation of tail gas utilizes of vitamin B6 新发药业有限公司 2019-06-04 CN claimed
CN-107849071-A antiviral β amino acid ester phosphorodiamidate compounds 默沙东公司 2018-03-27 CN claimed
CN-106244654-A A kind of enzyme transforming process prepares the method for L alanyl L alanine 精晶药业股份有限公司 2016-12-21 CN claimed
CN-119371422-A Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2025-01-28 CN disclosed
CN-114269744-B Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2024-10-18 CN disclosed
EP-3172375-B1 FIBROUS SUPPORT COMPRISING PARTICLES CONTAINING A PARTIALLY WATER-SOLUBLE ACTIVE AGENT, PARTICLES, AND METHODS FOR PRODUCING SAID PARTICLES SATISLOH AG (CH) 2024-03-13 EP disclosed
EP-3334743-B1 ANTIVIRAL BETA-AMINO ACID ESTER PHOSPHODIAMIDE COMPOUNDS MERCK SHARP & DOHME LLC (US) 2023-11-29 EP disclosed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 EP disclosed
CN-114269744-A Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2022-04-01 CN disclosed
US-11267844-B2 Spirothietane nucleosides JANSSEN PHARMACEUTICA NV (BE) 2022-03-08 US disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed
EP-0696280-A1 SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS MERRELL DOW PHARMA (US) 1996-02-14 EP disclosed
EP-0532664-B1 SUPPORTED CHIRAL LIQUID MEMBRANE FOR THE SEPARATION OF ENANTIOMERS RES CORP TECHNOLOGIES INC (US) 1996-02-14 EP disclosed
WO-1994026735-A1 SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-11-24 WO disclosed
US-4246424-A IN PRESENCE OF ALKALI METAL AND POLYCYCLIC AROMATIC HYDROCARBON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-20 US disclosed
US-4158016-A CONTACTING WITH AN ALKALI METAL POLYCYCLIC AROMATIC HYDROCARBON CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-06-12 US disclosed
US-3970700-A Racemization of optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267844-B2 Spirothietane nucleosides SAMHD1, SLC28A1, SLC28A2 ALDH1A1 521/4885ATM 3544/4885TSHR 4528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.