Sugi Predict

Sugi Predict / Compounds / SCHEMBL7181783

SCHEMBL7181783

SCHEMBL7181783

CCCCOC(=O)[C@@H](C)N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.54
▸ ATM Q13315 1/20 0.50
▸ TSHR P16473 5/20 0.47
▸ HPGD P15428 2/20 0.47
▸ HCAR2 Q8TDS4 1/20 0.44
▸ NAAA Q02083 1/20 0.43
▸ LMNA P02545 2/20 0.43
▸ CYP1A2 P05177 2/20 0.43
▸ CYP2C19 P33261 2/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ PDE4D Q08499 1/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ SLC15A1 P46059 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213810 1.00 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL624749 1.00 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL4380145 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL213809 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL4731637 0.98 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL18378673 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL4672442 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL253585 0.93 NAAA (0.52) ALDH1A1ATMTSHRHCAR2NAAA
SCHEMBL2382560 0.92 ALDH1A1 (0.47) ALDH1A1ATMTSHRHPGDHCAR2
Hydrochloric Acid SCHEMBL23510790 0.91 NAAA (0.50) ALDH1A1ATMTSHRHCAR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250288583-A1 Treatment of Mucus Hypersecretion ALTA RESEARCH, LLC 2025-09-18 — — US disclosed
EP-3386512-B1 ANTIVIRAL PHOSPHODIAMIDE PRODRUGS OF TENOFOVIR MERCK SHARP & DOHME LLC (US) 2023-11-22 — — EP disclosed
US-10745428-B2 Antiviral phosphodiamide prodrugs of tenofovir IDENIX PHARMACEUTICALS LLC (US) 2020-08-18 — — US disclosed
CN-111356456-A 2-arylsulfonamido-iV-arylacetamide derived Stat3 inhibitor 夏威夷大学 2020-06-30 — — CN disclosed
US-9796660-B2 Gamma amino acid building blocks WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-10-24 — — US disclosed
US-9657057-B2 Dipeptide and tripeptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2017-05-23 — — US disclosed
CN-106167504-A Acyclonucleosides phosphamide D amino acid ester derivative and the preparation of salt thereof and in the application of anti-virus aspect 洛阳聚慧医药科技有限公司 2016-11-30 — — CN disclosed
US-20160280632-A1 GAMMA AMINO ACID BUILDING BLOCKS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-09-29 — — US disclosed
US-9382291-B2 Gamma amino acid building blocks WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-07-05 — — US disclosed
US-20160031934-A1 DIPEPTIDE AND TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. 2016-02-04 — — US disclosed
US-20150148523-A1 GAMMA AMINO ACID BUILDING BLOCKS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-05-28 — — US disclosed
WO-2014152127-A1 DIPEPTIDE AND TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. (US) 2014-09-25 — — WO disclosed
US-8664356-B2 Gamma amino acid building blocks WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-03-04 — — US disclosed
US-20120282180-A1 Compounds with Matrix-Metalloproteinase Inhibitory Activity and Imaging Agents Thereof SIEMENS MEDICAL SOLUTIONS USA, INC. 2012-11-08 — — US disclosed
US-20110118440-A1 GAMMA AMINO ACID BUILDING BLOCKS WISCONSIN ALUMNI RESEARCH FOUNDATION 2011-05-19 — — US disclosed
WO-2011047190-A1 GAMMA AMINO ACID BUILDING BLOCKS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-21 — — WO disclosed
EP-1322596-A1 ZWITTERIONIC TACHYKININ RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 2003-07-02 — — EP disclosed
WO-2002024629-A1 ZWITTERIONIC TACHYKININ RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2002-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282180-A1 Compounds with Matrix-Metalloproteinase Inhibitory Activity and Imaging Agents Thereof MMP1, MMP17, MMP25 ALDH1A1 404/4885ATM 4582/4885TSHR 4062/4885
US-20110118440-A1 GAMMA AMINO ACID BUILDING BLOCKS DNPEP, QPCT, ANPEP ALDH1A1 904/4885ATM 3328/4885TSHR 4427/4885
US-20160031934-A1 DIPEPTIDE AND TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS PREP, PEPD, DNPEP ALDH1A1 2356/4885ATM 4364/4885TSHR 3244/4885
US-20150148523-A1 GAMMA AMINO ACID BUILDING BLOCKS DNPEP, QPCT, ANPEP ALDH1A1 904/4885ATM 3328/4885TSHR 4427/4885
US-10745428-B2 Antiviral phosphodiamide prodrugs of tenofovir PNP, TYMP, PPA1 ALDH1A1 3212/4885ATM 3682/4885TSHR 4347/4885
US-20160280632-A1 GAMMA AMINO ACID BUILDING BLOCKS DNPEP, QPCT, ANPEP ALDH1A1 904/4885ATM 3328/4885TSHR 4427/4885
US-20250288583-A1 Treatment of Mucus Hypersecretion TRPM8, GPR18, OPRL1 ALDH1A1 4313/4885ATM 2687/4885TSHR 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.