Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.32 |
| ▸ | CCND1 | P24385 | 3/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248585 | 1.00 | GABBR2 (0.46) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL6225865 | 0.80 | ALDH1A1 (0.39) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL6225863 | 0.80 | ALDH1A1 (0.39) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL7439427 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4E | |
| SCHEMBL5858750 | 0.77 | ALDH1A1 (0.43) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL5858751 | 0.77 | ALDH1A1 (0.43) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL7565552 | 0.73 | P4HTM (0.50) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL23677885 | 0.72 | TUBB4A (0.51) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL6226087 | 0.72 | ALDH1A1 (0.39) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL31193475 | 0.72 | GRM5 (0.56) | GABBR2GABBR1ALDH1A1TRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513856-A1 | 3-DESCLADINOSYL-6-O-CARBAMOYL AND 6-O-CARBONOYL MACROLIDE ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-03-16 | — | — | EP | disclosed |
| US-6825172-B2 | BACTERICIDES; AGAINST GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | JANSSEN PHARMACEUTICA, NV (BE) | 2004-11-30 | — | — | US | disclosed |
| US-20040018994-A1 | 3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-01-29 | — | — | US | disclosed |
| WO-2003102010-A1 | 3-DESCLADINOSYL-6-O-CARBAMOYL AND 6-O-CARBONOYL MACROLIDE ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018994-A1 | 3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents | CHCHD6, MRPL21, MRPS18B | GABBR2 4756/4885GABBR1 4775/4885ALDH1A1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.