Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 9/20 | 0.46 |
| ▸ | CD74 | P04233 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579498 | 0.90 | SCN1A (0.48) | SCN1ASCN5ASCN9ACTSSCD74 | |
| SCHEMBL6250611 | 0.81 | OPRM1 (0.56) | — | |
| SCHEMBL4714933 | 0.79 | CTSS (0.53) | SCN1ASCN5ASCN9ACTSSMEN1 | |
| SCHEMBL31290018 | 0.78 | NOTUM (0.50) | SCN1ASCN5ASCN9ACTSSMEN1 | |
| Trifluoroacetic Acid SCHEMBL6249351 | 0.78 | CACNA1B (0.45) | SCN1ASCN5ASCN9ACTSSCD74 | |
| SCHEMBL6247970 | 0.76 | OXTR (0.49) | CTSSCD74OXTR | |
| SCHEMBL7346980 | 0.76 | OPRM1 (0.50) | SCN1ASCN5ASCN9ACTSSMEN1 | |
| SCHEMBL11009319 | 0.75 | OPRM1 (0.52) | SCN1ASCN5ASCN9ACTSSMEN1 | |
| SCHEMBL6249272 | 0.73 | TNKS (0.41) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4717172 | 0.72 | NOTUM (0.44) | SCN1ASCN5ASCN9ACTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256575-B1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6916822-B2 | Phenoxyalkylamine derivatives useful as opioid δ receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1256575-A1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | OPRM1, OPRK1, OPRD1 | SCN1A 337/4885SCN5A 303/4885SCN9A 393/4885 |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | OPRD1, OPRM1, OPRK1 | SCN1A 174/4885SCN5A 303/4885SCN9A 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.