Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111104 | 0.99 | L3MBTL1 (0.51) | L3MBTL1ACHEHTR1ASLC6A2SLC6A4 | |
| SCHEMBL5561359 | 0.95 | HTR1A (0.48) | L3MBTL1ACHEHTR1ASLC6A2SLC6A4 | |
| SCHEMBL6252228 | 0.84 | L3MBTL1 (0.54) | L3MBTL1ACHEADRA1DADRA1A | |
| SCHEMBL6253311 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ACHEADRA1DADRA1A | |
| SCHEMBL14585900 | 0.82 | ADRA1B (0.51) | HTR1ASLC6A2SLC6A4SLC6A3ADRA1D | |
| SCHEMBL14458720 | 0.81 | ADRA1B (0.49) | L3MBTL1ADRA1DADRA1A | |
| SCHEMBL6111320 | 0.79 | HTR1A (0.46) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14355968 | 0.79 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6253602 | 0.78 | ADRA1B (0.47) | L3MBTL1ADRA1DADRA1A | |
| SCHEMBL14458725 | 0.78 | ADRA1B (0.47) | L3MBTL1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054278-A1 | SUBSTITUTED N-BENZYL-LACTAM DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-16 | — | — | WO | disclosed |