Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 5/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253311 | 0.96 | L3MBTL1 (0.51) | ADRA1BADRA1AADRA1DL3MBTL1 | |
| SCHEMBL6252228 | 0.95 | L3MBTL1 (0.54) | ADRA1AADRA1DL3MBTL1 | |
| SCHEMBL14458720 | 0.86 | ADRA1B (0.49) | ADRA1BADRA1AADRA1DL3MBTL1 | |
| SCHEMBL5561359 | 0.83 | HTR1A (0.48) | ADRA1BADRA1AADRA1DL3MBTL1 | |
| SCHEMBL14458725 | 0.83 | ADRA1B (0.47) | ADRA1BADRA1AADRA1DL3MBTL1 | |
| SCHEMBL6111104 | 0.80 | L3MBTL1 (0.51) | ADRA1AADRA1DL3MBTL1 | |
| SCHEMBL6249596 | 0.78 | L3MBTL1 (0.54) | ADRA1AADRA1DL3MBTL1 | |
| SCHEMBL14458690 | 0.78 | ADRA1A (0.43) | ADRA1BADRA1AADRA1DL3MBTL1 | |
| SCHEMBL6252010 | 0.76 | L3MBTL1 (0.43) | ADRA1BL3MBTL1 | |
| SCHEMBL14585899 | 0.74 | PLA2G7 (0.46) | ADRA1BADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054278-A1 | SUBSTITUTED N-BENZYL-LACTAM DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-16 | — | — | WO | disclosed |