Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253311 | 0.99 | L3MBTL1 (0.51) | L3MBTL1ADRA1DADRA1AACHE | |
| SCHEMBL6253602 | 0.95 | ADRA1B (0.47) | L3MBTL1ADRA1DADRA1A | |
| SCHEMBL6249596 | 0.84 | L3MBTL1 (0.54) | L3MBTL1ADRA1DADRA1AACHE | |
| SCHEMBL6111104 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ADRA1DADRA1AACHE | |
| SCHEMBL14458720 | 0.81 | ADRA1B (0.49) | L3MBTL1ADRA1DADRA1A | |
| SCHEMBL14458725 | 0.78 | ADRA1B (0.47) | L3MBTL1ADRA1DADRA1A | |
| SCHEMBL5561359 | 0.78 | HTR1A (0.48) | L3MBTL1ADRA1DADRA1AACHE | |
| SCHEMBL6252224 | 0.77 | L3MBTL1 (0.51) | L3MBTL1ACHEHRH3 | |
| SCHEMBL1111741 | 0.76 | ALDH1A1 (0.47) | — | |
| SCHEMBL6251892 | 0.75 | L3MBTL1 (0.49) | L3MBTL1ACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054278-A1 | SUBSTITUTED N-BENZYL-LACTAM DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-16 | — | — | WO | disclosed |