Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625279 | 0.89 | TRPV3 (0.53) | TRPV3NR1I2HDAC3HDAC1HDAC2 | |
| SCHEMBL625858 | 0.88 | TRPV3 (0.66) | TRPV3NR1I2GRIN2BNPY5RKDM4E | |
| SCHEMBL624516 | 0.87 | TRPV3 (0.58) | TRPV3NR1I2KDM4EOPRM1OPRD1 | |
| SCHEMBL625711 | 0.86 | TRPV3 (0.55) | TRPV3NR1I2HDAC3HDAC1HDAC2 | |
| SCHEMBL626324 | 0.86 | TRPV3 (0.52) | TRPV3NR1I2HDAC3HDAC1HDAC2 | |
| SCHEMBL625365 | 0.86 | NR1I2 (0.51) | TRPV3NR1I2KDM4EOPRM1OPRD1 | |
| SCHEMBL624525 | 0.83 | NR1I2 (0.72) | TRPV3NR1I2HDAC6 | |
| SCHEMBL626364 | 0.81 | TRPV3 (0.80) | TRPV3NR1I2HDAC1LMNAL3MBTL1 | |
| SCHEMBL14893638 | 0.79 | NR1I2 (0.49) | TRPV3NR1I2KDM4EOPRM1OPRD1 | |
| SCHEMBL14893888 | 0.77 | NR1I2 (0.49) | TRPV3NR1I2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116325392-B | Wavelength-variable light source and control method thereof | 日本电信电话株式会社 | 2025-05-30 | — | — | CN | claimed |
| CN-119094492-A | Method for crossing network to penetrate local area network gateway | 王博靖 | 2024-12-06 | — | — | CN | claimed |
| CN-114189491-B | Method for backuping and restoring Exchange mail server without agent | 成都傲梅科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-112929418-B | Rapid IO high-speed communication method and system based on publish-subscribe | 华东计算技术研究所（中国电子科技集团公司第三十二研究所） | 2023-03-14 | — | — | CN | claimed |
| US-9156788-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2015-10-13 | — | — | US | claimed |
| EP-2603490-A1 | NOVEL TRPV3 MODULATORS | AbbVie Inc. (US) | 2013-06-19 | — | — | EP | claimed |
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-06-13 | — | — | US | claimed |
| WO-2012019315-A1 | NOVEL TRPV3 MODULATORS | ABBOTT LABORATORIES (US) | 2012-02-16 | — | — | WO | claimed |
| US-12481540-B2 | Techniques for resource discovery while building data centers | ORACLE INTERNATIONAL CORPORATION (US) | 2025-11-25 | — | — | US | disclosed |
| WO-2025215454-A1 | TASK PROCESSING METHOD AND SYSTEM, MODEL TRAINING TASK PROCESSING METHOD, AND COMPUTING DEVICE | 云智能资产控股（新加坡）私人股份有限公司 | 2025-10-16 | — | — | WO | disclosed |
| CN-119315703-A | Meteorological information-based power grid dynamic monitoring and early warning method, system and storage medium | 广州极能信息技术有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119292974-A | Method for transmitting and receiving big data through TSI721 in Linux system | 华东计算技术研究所（中国电子科技集团公司第三十二研究所） | 2025-01-10 | — | — | CN | disclosed |
| CN-119250191-A | Knowledge graph construction method, device, equipment and medium based on artificial intelligence | 中国平安财产保险股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119130525-A | Sales policy generation method and device, program product and storage medium | 中国建设银行股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-2603490-A1 | NOVEL TRPV3 MODULATORS | AbbVie Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130131036-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2013062966-A2 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013062964-A2 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012019315-A1 | NOVEL TRPV3 MODULATORS | ABBOTT LABORATORIES (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131036-A1 | NOVEL TRPV3 MODULATORS | TRPV3, TRPV4, TRPV5 | TRPV3 1/4885NR1I2 210/4885GRIN2B 557/4885 |
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | TRPV3, TRPV4, TRPV5 | TRPV3 1/4885NR1I2 219/4885GRIN2B 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.