SCHEMBL626324

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL625908	0.89	TRPV3 (0.65)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL624975	0.86	TRPV3 (0.52)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL625279	0.86	TRPV3 (0.53)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL625711	0.85	TRPV3 (0.55)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL624714	0.82	NR1I2 (0.56)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL626364	0.81	TRPV3 (0.80)	TRPV3NR1I2HDAC1LMNAALDH1A1
	SCHEMBL14893533	0.79	TRPV3 (0.42)	TRPV3NR1I2HDAC6HDAC3HDAC1
	SCHEMBL624516	0.79	TRPV3 (0.58)	TRPV3NR1I2OPRM1OPRD1OPRK1
	SCHEMBL625365	0.78	NR1I2 (0.51)	TRPV3NR1I2OPRM1OPRD1OPRK1
	SCHEMBL14893180	0.76	TRPV3 (0.45)	TRPV3NR1I2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.