Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161941 | 0.87 | TSHR (0.42) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL4981584 | 0.84 | TSHR (0.40) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL302003 | 0.82 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL16805856 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL17522064 | 0.81 | ALDH1A1 (0.43) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL4818353 | 0.80 | TSHR (0.40) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL962842 | 0.78 | TSHR (0.48) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL22215980 | 0.78 | TSHR (0.41) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL3675723 | 0.78 | THRB (0.43) | TSHRALDH1A1THRBTDP1MGAM | |
| SCHEMBL51592 | 0.76 | TSHR (0.50) | TSHRALDH1A1THRBTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128678-A2 | COMPOSITIONS AND METHODS FOR RESTRUCTURING CHEMICALLY TREATED HAIR | L'OREAL (FR) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018093575-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE QUALITY OF CHEMICALLY TREATED HAIR | L'OREAL (FR) | 2018-05-24 | — | — | WO | disclosed |
| WO-2012021472-A2 | COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES | L'OREAL S. A. (FR) | 2012-02-16 | — | — | WO | disclosed |
| EP-1855643-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2007-11-21 | — | — | EP | disclosed |
| EP-1855638-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'Oréal (FR) | 2007-11-21 | — | — | EP | disclosed |
| US-20060230546-A1 | Anhydrous composition in the form of a film comprising at least one film-forming polymer and at least one oxidation dye, preparation, and dyeing process | L'OREAL S.A. (FR) | 2006-10-19 | — | — | US | disclosed |
| WO-2006089809-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006089806-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'ORÉAL (FR) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060230546-A1 | Anhydrous composition in the form of a film comprising at least one film-forming polymer and at least one oxidation dye, preparation, and dyeing process | KRT18, DSG1, DSP | TSHR 4877/4885ALDH1A1 93/4885THRB 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.