Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675723 | 0.84 | THRB (0.43) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL625056 | 0.80 | TSHR (0.41) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL17717777 | 0.79 | TSHR (0.38) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL13730475 | 0.78 | TSHR (0.49) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL7161941 | 0.78 | TSHR (0.42) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL16267594 | 0.77 | TSHR (0.36) | TSHRALDH1A1THRBEGLN1 | |
| SCHEMBL13732412 | 0.77 | HTR1A (0.45) | ALDH1A1CYP2D6TDP1HTR1ASCN1A | |
| SCHEMBL13730855 | 0.76 | TSHR (0.54) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL14353640 | 0.76 | TSHR (0.54) | TSHRALDH1A1THRBCYP2D6TDP1 | |
| SCHEMBL13732043 | 0.76 | TSHR (0.54) | TSHRALDH1A1THRBCYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638192-B1 | COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID OR BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS | OREAL (FR) | 2025-04-02 | — | — | EP | disclosed |
| US-11975093-B2 | Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain | L'OREAL (FR) | 2024-05-07 | — | — | US | disclosed |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | L'OREAL (FR) | 2023-11-21 | — | — | US | disclosed |
| EP-2806851-B2 | COMPOSITION COMPRISING AT LEAST ONE SPECIFIC ALKOXYSILANE POLYMER | OREAL (FR) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021133971-A1 | MASCARA BASED ON POLYPHENOL AND FILM FORMING POLYMER AND METHODS FOR MAKING UP EYELASHES | L'OREAL (FR) | 2021-07-01 | — | — | WO | disclosed |
| US-7335348-B2 | Hairstyling composition which makes possible remodelling of the hairstyle and process for remodelling the hairstyle using such a composition | L'OREAL (FR) | 2008-02-26 | — | — | US | disclosed |
| US-20050208005-A1 | Cosmetic composition comprising particles having a core-shell structure | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | disclosed |
| US-20050186151-A1 | Cosmetic composition comprising stabilized and optionally coated metal particles | L'OREAL S.A. (FR) | 2005-08-25 | — | — | US | disclosed |
| US-20050112154-A1 | Cosmetic composition comprising particles having a core-shell structure | L'OREAL S.A. (FR) | 2005-05-26 | — | — | US | disclosed |
| US-20050112155-A1 | Cosmetic composition comprising a passivated and optionally coated metal particles | L'OREAL S.A. (FR) | 2005-05-26 | — | — | US | disclosed |
| US-20030143180-A1 | Hairstyling composition which makes possible remodelling of the hairstyle and process for remodelling the hairstyle using such a composition | L'OREAL | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143180-A1 | Hairstyling composition which makes possible remodelling of the hairstyle and process for remodelling the hairstyle using such a composition | KRT18, PIK3C3, FKBP5 | TSHR 3293/4885ALDH1A1 4801/4885THRB 3561/4885 |
| US-20050186151-A1 | Cosmetic composition comprising stabilized and optionally coated metal particles | KRT18, CUTA, LAGE3 | TSHR 2869/4885ALDH1A1 1600/4885THRB 3883/4885 |
| US-20050112155-A1 | Cosmetic composition comprising a passivated and optionally coated metal particles | CUTA, KRT18, TYR | TSHR 943/4885ALDH1A1 180/4885THRB 2921/4885 |
| US-11975093-B2 | Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain | PRKCA, PRKCH, CUTA | TSHR 4639/4885ALDH1A1 4493/4885THRB 3971/4885 |
| US-20050112154-A1 | Cosmetic composition comprising particles having a core-shell structure | KRT18, CUTA, DSG1 | TSHR 2948/4885ALDH1A1 743/4885THRB 3503/4885 |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | PIK3CA, PTEN, PIK3CG | TSHR 3897/4885ALDH1A1 4755/4885THRB 3892/4885 |
| US-20050208005-A1 | Cosmetic composition comprising particles having a core-shell structure | KRT18, CUTA, DSG1 | TSHR 2974/4885ALDH1A1 869/4885THRB 3814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.