Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899652 | 0.71 | BCL2 (0.37) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13503079 | 0.71 | CRHBP (0.37) | ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL11710268 | 0.71 | CRHBP (0.37) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL864536 | 0.71 | CRHBP (0.37) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL27913228 | 0.71 | CRHBP (0.40) | ALDH1A1HPGDHCAR2MAPTSMN1; SMN2 | |
| SCHEMBL28159300 | 0.70 | ERN1 (0.41) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL6806663 | 0.69 | LMNA (0.42) | ALDH1A1HPGDALOX15HSD17B10HCAR2 | |
| SCHEMBL3869264 | 0.69 | ATM (0.47) | ALDH1A1HPGDALOX15HSD17B10MGAM | |
| SCHEMBL3887568 | 0.67 | CRHBP (0.34) | ALDH1A1KDM4EGAACRHBPCRHR2 | |
| SCHEMBL10865681 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HPGDALOX15MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242250-A | Preparation method of 2-quinoxaline methylene hydrazino cyanoacetic acid-N1-oxide | UNIV CHINA AGRICULTURAL | 2013-08-14 | — | — | CN | claimed |
| EP-1558587-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | Pfizer Products Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-20040097554-A1 | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents | PFIZER INC | 2004-05-20 | — | — | US | claimed |
| WO-2004039787-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | claimed |
| CN-103242250-A | Preparation method of 2-quinoxaline methylene hydrazino cyanoacetic acid-N1-oxide | UNIV CHINA AGRICULTURAL | 2013-08-14 | — | — | CN | disclosed |
| EP-1558587-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | Pfizer Products Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20040097554-A1 | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents | PFIZER INC | 2004-05-20 | — | — | US | disclosed |
| WO-2004039787-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097554-A1 | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents | CCR1, HCAR1, CCR3 | ALDH1A1 303/4885HPGD 1924/4885ALOX15 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.