Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503079 | 0.76 | CRHBP (0.37) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL27913228 | 0.76 | CRHBP (0.40) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL11710268 | 0.76 | CRHBP (0.37) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL3887568 | 0.76 | CRHBP (0.34) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL4899652 | 0.73 | BCL2 (0.37) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL28159300 | 0.72 | ERN1 (0.41) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| Methane SCHEMBL27899889 | 0.71 | CRHBP (0.36) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL6251001 | 0.71 | ALDH1A1 (0.43) | CRHBPCRHR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29359446 | 0.69 | CRHBP (0.61) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL51330 | 0.69 | CRHBP (0.61) | CRHBPCRHR2KEAP1NFE2L2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114493-A1 | LANTHANIDE METAL COMPLEXES USEFUL IN TREATING CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-10-07 | — | — | WO | claimed |
| US-3971725-A | 2-Mercaptoquinoxaline-1-oxides, salts thereof and 2-(1-oxoquinoxalinyl)disulfides in detergent compositions | COLGATE-PALMOLIVE COMPANY (US) | 1976-07-27 | — | — | US | claimed |
| US-8338338-B2 | Formulations comprising triazoles and alkoxylated amines | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-12-25 | — | — | US | disclosed |
| US-20120077792-A1 | LANTHANIDE METAL COMPLEXES USEFUL IN TREATING CANCER | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-03-29 | — | — | US | disclosed |
| US-20100099724-A1 | Formulations Comprising Triazoles and Alkoxylated Amines | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-04-22 | — | — | US | disclosed |
| US-7662748-B2 | Such as azaconazole, bromuconazole, and N,N',N'-tris(2-hydroxyethyl)-N-cocoalkyl-1,3-diamino-propane; kits; for protection of crops, plants, fruits, seeds, wood products, thatch, biodegradable material and textiles | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-02-16 | — | — | US | disclosed |
| WO-2008140469-A2 | ANTIMICROBIAL COMPOSITIONS, METHODS AND SYSTEMS | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080033026-A1 | Antimicrobial compositions, methods and systems | ELEVANCE RENEWABLE SCIENCES, INC. | 2008-02-07 | — | — | US | disclosed |
| EP-1473996-B1 | FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES | JANSSEN PHARMACEUTICA NV (BE) | 2006-04-26 | — | — | EP | disclosed |
| US-20050124690-A1 | Pharmaceutical composition for the treatment of seborrhea containing 4-hydroxy-5-methoxy-4-[2-methyl-3(3-methyl-2-butenyl)-2-oxiranyl]-1-oxaspiro[2,5]octan-6-one | MYCOPLUS CO., LTD. (KR) | 2005-06-09 | — | — | US | disclosed |
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | AKZO NOBEL CHEMICALS BV (NL) | 2005-04-14 | — | — | US | disclosed |
| EP-0148526-A1 | Water-dilutable wood-preserving liquids | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-07-17 | — | — | EP | disclosed |
| EP-0038109-B1 | AGENTS AND METHOD FOR THE PROTECTION OF COATINGS AND WOOD AND OTHER NON-LIVING ORGANIC SUBSTRATES FROM DETERIORATION BY MICRO-ORGANISMS | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-08-29 | — | — | EP | disclosed |
| US-4364949-A | BACTERICIDE, FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4339462-A | BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0038109-A2 | Agents and method for the protection of coatings and wood and other non-living organic substrates from deterioration by micro-organisms | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-10-21 | — | — | EP | disclosed |
| US-4268693-A | 3-Hydroxydiphenyl ethers | CIBA-GEIGY CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |
| US-3971725-A | 2-Mercaptoquinoxaline-1-oxides, salts thereof and 2-(1-oxoquinoxalinyl)disulfides in detergent compositions | COLGATE-PALMOLIVE COMPANY (US) | 1976-07-27 | — | — | US | disclosed |
| US-3971725-A | 2-Mercaptoquinoxaline-1-oxides, salts thereof and 2-(1-oxoquinoxalinyl)disulfides in detergent compositions | COLGATE-PALMOLIVE COMPANY (US) | 1976-07-27 | — | — | US | disclosed |
| US-3852443-A | 2-MERCAPTOQUINOXALINE-1-OXIDES, SALTS THEREOF AND-(1-OXOQUINOXALINYL) DISULFIDES FOR TREATING HAIR AND SKIN | COLGATE PALMOLIVE CO | 1974-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077792-A1 | LANTHANIDE METAL COMPLEXES USEFUL IN TREATING CANCER | IAPP, RNASE1, LETM1 | CRHBP 4300/4885CRHR2 4334/4885KEAP1 764/4885 |
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | ALKBH3, TYR, NAT1 | CRHBP 4785/4885CRHR2 4224/4885KEAP1 147/4885 |
| US-20080033026-A1 | Antimicrobial compositions, methods and systems | DHCR7, SPOUT1, DSTN | CRHBP 4649/4885CRHR2 4136/4885KEAP1 1112/4885 |
| US-20100099724-A1 | Formulations Comprising Triazoles and Alkoxylated Amines | ALKBH3, TYR, NAT1 | CRHBP 4785/4885CRHR2 4224/4885KEAP1 147/4885 |
| US-20050124690-A1 | Pharmaceutical composition for the treatment of seborrhea containing 4-hydroxy-5-methoxy-4-[2-methyl-3(3-methyl-2-butenyl)-2-oxiranyl]-1-oxaspiro[2,5]octan-6-one | SRD5A2, CYP17A1, SRD5A1 | CRHBP 2879/4885CRHR2 1773/4885KEAP1 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.