Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251892 | 0.96 | L3MBTL1 (0.49) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL6252224 | 0.95 | L3MBTL1 (0.51) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL14458709 | 0.86 | L3MBTL1 (0.46) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL14458715 | 0.84 | L3MBTL1 (0.43) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL6109530 | 0.84 | SLC6A2 (0.46) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL6109813 | 0.81 | ACHE (0.49) | L3MBTL1KMT2AMAPK1ACHESMN1; SMN2 | |
| SCHEMBL6251645 | 0.80 | L3MBTL1 (0.51) | L3MBTL1KMT2AMAPK1ACHEGAA | |
| SCHEMBL14458711 | 0.79 | L3MBTL1 (0.39) | L3MBTL1KMT2AMAPK1CHRM2CHRM4 | |
| SCHEMBL6253602 | 0.76 | ADRA1B (0.47) | L3MBTL1ADRA1B | |
| SCHEMBL14537171 | 0.75 | GPR119 (0.47) | KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054278-A1 | SUBSTITUTED N-BENZYL-LACTAM DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-16 | — | — | WO | disclosed |