SCHEMBL625220

SCHEMBL625220

OCCc1ccccc1F

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.62
AOC3 Q16853 1/20 0.50
MPO P05164 4/20 0.48
IDO1 P14902 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
DAO P14920 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
MAOB P27338 1/20 0.42
SLC6A4 P31645 1/20 0.42
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29796478 1.00 TAAR1 (0.62) TAAR1AOC3MPOIDO1TDP1
SCHEMBL6987706 0.86 TAAR1 (0.52) TAAR1AOC3MPOLMNAMAOB
SCHEMBL80668 0.86 TAAR1 (0.58) TAAR1AOC3MPOIDO1DAO
SCHEMBL31069259 0.86 TAAR1 (0.58) TAAR1AOC3MPOIDO1DAO
SCHEMBL2956567 0.84 TAAR1 (0.56) TAAR1AOC3MPOIDO1DAO
SCHEMBL8526001 0.84 TAAR1 (0.75) TAAR1AOC3MPOIDO1DAO
SCHEMBL15022605 0.82 TAAR1 (0.54) TAAR1AOC3MPOIDO1DAO
SCHEMBL2339012 0.81 TAAR1 (0.41) TAAR1AOC3MPOIDO1TDP1
SCHEMBL29471378 0.81 TAAR1 (0.41) TAAR1AOC3MPOIDO1TDP1
SCHEMBL31203 0.81 TDP1 (0.55) TAAR1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539039-A Method for synthesizing chiral fluorophenethyl alcohol by photo-enzyme catalysis 广东省科学院微生物研究所(广东省微生物分析检测中心) 2022-05-27 CN claimed
CN-105039430-A Method for producing (S)-fluobenzene ethanol through candida UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-11 CN claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 US disclosed
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 US disclosed
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 US disclosed
US-12264134-B2 Substituted piperazine amide compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors MERCK SHARP & DOHME LLC (US) 2025-04-01 US disclosed
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2025-03-27 US disclosed
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS HOFFMANN-LA ROCHE INC. (US) 2025-03-06 US disclosed
CN-119212989-A Pyrazole derivatives as STING agonists 豪夫迈·罗氏有限公司 2024-12-27 CN disclosed
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2024-12-12 US disclosed
EP-0699180-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1996-03-06 EP disclosed
US-5466554-A Toner compositions with modified polyester resins XEROX CORPORATION (US) 1995-11-14 US disclosed
EP-0670720-A1 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-09-13 EP disclosed
US-5378726-A Insecticide, parasiticide NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1995-01-03 US disclosed
CN-1095710-A Enzyme Inhibitors WELLCOME FOUND (GB) 1994-11-30 CN disclosed
WO-1994026692-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-11-24 WO disclosed
WO-1994026693-A1 BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS THE WELLCOME FOUNDATION LIMITED (GB) 1994-11-24 WO disclosed
WO-1994012165-A2 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1994-06-09 WO disclosed
CN-1069882-A The Compounds and methods for that suppresses HIV and correlated virus MEDIVIR AB (CH) 1993-03-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS ERG28, DPM1, CYP51A1 TAAR1 3783/4885AOC3 450/4885MPO 1597/4885
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885AOC3 847/4885MPO 445/4885
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF ADH1C, HTR6, CNR1 TAAR1 97/4885AOC3 124/4885MPO 1840/4885
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C TAAR1 3002/4885AOC3 3829/4885MPO 2186/4885
US-12630566-B2 KRas G12D inhibitors KRAS, NRAS, HRAS TAAR1 4774/4885AOC3 4826/4885MPO 4031/4885
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS STING1, CGAS, MAVS TAAR1 630/4885AOC3 3269/4885MPO 3285/4885
US-12264134-B2 Substituted piperazine amide compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors IDO1, IDO2, AADAC TAAR1 1503/4885AOC3 1091/4885MPO 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.