Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083535 | 0.86 | DDX3X (0.49) | MCHR1MAPTMEN1KMT2AHDAC3 | |
| SCHEMBL10083543 | 0.81 | MCHR1 (0.47) | MCHR1MCHR2GAAALOX15 | |
| SCHEMBL10083554 | 0.80 | KMT2A (0.44) | MCHR1MAPTALDH1A1KMT2AHDAC3 | |
| SCHEMBL12503486 | 0.79 | KDM1A (0.40) | MCHR1HDAC3HDAC1GAAHPGD | |
| SCHEMBL624200 | 0.79 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL623943 | 0.78 | MEN1 (0.51) | MCHR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL624314 | 0.77 | NPC1 (0.59) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL625028 | 0.77 | DYRK1A (0.52) | MCHR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL625245 | 0.77 | MEN1 (0.58) | MAPTMEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL627332 | 0.76 | MAPT (0.49) | MCHR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |