Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625245 | 0.83 | MEN1 (0.58) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL624269 | 0.80 | HTT (0.47) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10083535 | 0.79 | DDX3X (0.49) | MAPTMEN1KMT2AMCHR1HDAC3 | |
| SCHEMBL625028 | 0.78 | DYRK1A (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL625901 | 0.78 | NPC1 (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10083543 | 0.77 | MCHR1 (0.47) | GAAMCHR1MCHR2 | |
| SCHEMBL625266 | 0.76 | MCHR1 (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL625958 | 0.76 | SMN1; SMN2 (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL623943 | 0.76 | MEN1 (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10083554 | 0.75 | KMT2A (0.44) | MAPTKMT2AALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |