Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625901 | 0.89 | NPC1 (0.57) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL625756 | 0.84 | CHRM4 (0.52) | DYRK1ATMIGD3ADORA1MEN1KMT2A | |
| SCHEMBL625106 | 0.81 | RAB9A (0.48) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL625958 | 0.80 | SMN1; SMN2 (0.60) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL10083535 | 0.80 | DDX3X (0.49) | MEN1KMT2AMAPTMCHR1 | |
| SCHEMBL624218 | 0.80 | KCNMA1 (0.53) | ADORA1MEN1KMT2ALMNAMAPT | |
| SCHEMBL625245 | 0.79 | MEN1 (0.58) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL623943 | 0.78 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL627332 | 0.78 | MAPT (0.49) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL10083543 | 0.78 | MCHR1 (0.47) | GAAPKMMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |