Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083543 | 0.83 | MCHR1 (0.47) | GAAMCHR1 | |
| SCHEMBL625106 | 0.82 | RAB9A (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL10083554 | 0.81 | KMT2A (0.44) | KMT2APOLBLMNAMAPTMCHR1 | |
| SCHEMBL10083535 | 0.81 | DDX3X (0.49) | MEN1KMT2AMAPTMCHR1 | |
| SCHEMBL624218 | 0.81 | KCNMA1 (0.53) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL624200 | 0.80 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL624314 | 0.79 | NPC1 (0.59) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL625245 | 0.78 | MEN1 (0.58) | MEN1KMT2APOLBLMNATSHR | |
| SCHEMBL624269 | 0.78 | HTT (0.47) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL625028 | 0.78 | DYRK1A (0.52) | MEN1KMT2AKDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |