SCHEMBL6253362

SCHEMBL6253362

CCCC1=C(C2CCCCC2)C=CC(=O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CTSK P43235 3/20 0.35
CTSS P25774 2/20 0.35
GRIN2D O15399 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
PTPRC P08575 1/20 0.31
PTPRF P10586 1/20 0.31
PTPN1 P18031 1/20 0.31
CDC25B P30305 1/20 0.31
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
ADORA2A P29274 2/20 0.31
ADORA2B P29275 2/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586976 0.68 ALOX5 (0.34) EPHX2ALDH1A1CNR1CNR2
SCHEMBL10704304 0.65 ACHE (0.40) ALDH1A1TSHRNPSR1
SCHEMBL7920879 0.60 EPHX2 (0.35) EPHX2CTSKCTSS
SCHEMBL29577475 0.59 EPHX2 (0.34) EPHX2CTSKCTSS
SCHEMBL4825129 0.59 HTR1D (0.43) EPHX2CTSKCTSS
SCHEMBL12333863 0.59 CTSK (0.42) EPHX2CTSKCTSSNPC1RAB9A
SCHEMBL5799228 0.58 CTSK (0.48) EPHX2CTSKCTSSADORA2AADORA2B
SCHEMBL4825135 0.57 SPHK1 (0.51) EPHX2
SCHEMBL14529345 0.57 DRD2 (0.45) ADORA2AADORA2BADORA1
SCHEMBL15255055 0.57 ERBB2 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed