Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253565 | 0.90 | CALM1 (0.37) | SIGMAR1CALM1LTA4HMEN1KMT2A | |
| SCHEMBL6251692 | 0.87 | SIGMAR1 (0.40) | SIGMAR1TLR8KCNH2HSD11B1CETP | |
| SCHEMBL6250272 | 0.83 | TP53 (0.41) | SIGMAR1CALM1LTA4H | |
| SCHEMBL1028776 | 0.81 | CALM1 (0.44) | SIGMAR1CALM1LTA4HSMN1; SMN2 | |
| SCHEMBL1025348 | 0.79 | NPC1 (0.32) | — | |
| SCHEMBL11022343 | 0.77 | — | — | |
| SCHEMBL6253344 | 0.77 | TAAR1 (0.37) | SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL6255606 | 0.75 | SIGMAR1 (0.42) | SIGMAR1CALM1MEN1KMT2A | |
| SCHEMBL6249661 | 0.73 | HSD11B1 (0.37) | SIGMAR1HSD11B1 | |
| SCHEMBL6253531 | 0.73 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926150-B1 | Production of alkali metal cyclopentadienylides and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylides | HONSHU CHEMICAL IND (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-6046346-A | Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0926150-A2 | Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | Honshu Chemical Industry Co. Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |