Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028776 | 0.82 | CALM1 (0.44) | SIGMAR1TAAR1SLC18A2MAOACALM1 | |
| SCHEMBL6250272 | 0.81 | TP53 (0.41) | SIGMAR1TAAR1SLC18A2CALM1CYP3A4 | |
| SCHEMBL6253565 | 0.78 | CALM1 (0.37) | SIGMAR1TAAR1SLC18A2CALM1MEN1 | |
| SCHEMBL6255340 | 0.76 | CALM1 (0.38) | SIGMAR1TAAR1SLC18A2SLC6A2MAOA | |
| SCHEMBL6253556 | 0.75 | SIGMAR1 (0.37) | SIGMAR1CALM1MEN1KMT2A | |
| SCHEMBL6251956 | 0.73 | CALM1 (0.42) | SIGMAR1TAAR1MAOACALM1CYP3A4 | |
| SCHEMBL6255348 | 0.69 | CALM1 (0.38) | SIGMAR1TAAR1SLC6A2CALM1CYP2D6 | |
| Isopropyl Alcohol SCHEMBL8627714 | 0.69 | SLC6A4 (0.38) | SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4 | |
| Isopropyl Alcohol SCHEMBL8628614 | 0.69 | LTA4H (0.33) | SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4 | |
| SCHEMBL27933498 | 0.69 | SLC6A2 (0.42) | SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926150-B1 | Production of alkali metal cyclopentadienylides and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylides | HONSHU CHEMICAL IND (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-6046346-A | Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0926150-A2 | Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | Honshu Chemical Industry Co. Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |