Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 10/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625391 | 0.80 | HASPIN (0.52) | CHEK1MAPTTHRB | |
| SCHEMBL624827 | 0.74 | MAPT (0.62) | F2RL3MAPTTHRB | |
| SCHEMBL626985 | 0.72 | PIK3CA (0.53) | MTOR | |
| SCHEMBL625797 | 0.70 | PIK3CA (0.53) | — | |
| SCHEMBL624035 | 0.68 | SMN1; SMN2 (0.40) | MAPTAR | |
| SCHEMBL27796786 | 0.67 | SLC2A1 (0.46) | LRRK2ATRATRIP | |
| SCHEMBL19509928 | 0.67 | F2RL3 (0.65) | F2RL3 | |
| SCHEMBL623944 | 0.66 | SMN1; SMN2 (0.40) | MAPTTHRBAR | |
| SCHEMBL3763593 | 0.65 | NOS1 (0.66) | LRRK2ATRATRIPMTORHRH4 | |
| SCHEMBL3092051 | 0.63 | LRRK2 (0.54) | LRRK2ATRATRIPMTORCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |