Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 14/20 | 0.43 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990221 | 0.83 | NMBR (0.48) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL6251031 | 0.77 | ALDH1A1 (0.37) | MAPTLMNAMEN1KMT2ASGK1 | |
| SCHEMBL6994303 | 0.77 | ALDH1A1 (0.37) | MAPTLMNAMEN1KMT2ASGK1 | |
| SCHEMBL6254281 | 0.77 | FPR1 (0.51) | MAPTLMNAMEN1KMT2AMAOB | |
| SCHEMBL6252251 | 0.73 | NMBR (0.48) | — | |
| SCHEMBL6253991 | 0.68 | ALDH1A1 (0.44) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL6253217 | 0.67 | MAPT (0.44) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6254308 | 0.66 | PGR (0.38) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL4080094 | 0.65 | MAPT (0.64) | MAPTLMNAMEN1KMT2AMAOB | |
| SCHEMBL10965397 | 0.65 | RAB9A (0.77) | MAPTLMNAMEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |