Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254422 | 0.75 | ERN1 (0.46) | ABL1ABCB1BCRERN1KMT2A | |
| SCHEMBL6253592 | 0.75 | ALDH1A1 (0.36) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL6254428 | 0.75 | ERN1 (0.46) | ABL1ABCB1BCRERN1KMT2A | |
| SCHEMBL6254711 | 0.71 | MEN1 (0.41) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL10903067 | 0.69 | KMT2A (0.44) | ABL1ABCB1BCRERN1KMT2A | |
| SCHEMBL8922938 | 0.69 | CYP19A1 (0.36) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL10903061 | 0.69 | KMT2A (0.44) | ABL1ABCB1BCRERN1KMT2A | |
| SCHEMBL3076853 | 0.68 | SMN1; SMN2 (0.39) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL2116504 | 0.68 | MEN1 (0.47) | KMT2AMEN1MAPTLMNAHSP90AA1 | |
| SCHEMBL1725585 | 0.67 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572704-A1 | PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | Pfizer Products Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20040127465-A1 | Novel phosphorus-containing derivatives | PFIZER INC | 2004-07-01 | — | — | US | disclosed |
| WO-2004055031-A1 | PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127465-A1 | Novel phosphorus-containing derivatives | SLC34A2, SLC34A1, SLC20A1 | ABL1 3867/4885ABCB1 484/4885BCR 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.