Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998686 | 0.81 | PTGS2 (0.47) | CYP19A1APPMAOBALDH1A1KDM4E | |
| SCHEMBL7501045 | 0.74 | LMNA (0.35) | CYP19A1MAOANPC1LMNARAB9A | |
| SCHEMBL1250328 | 0.74 | SRC (0.36) | — | |
| SCHEMBL915104 | 0.72 | FDPS (0.40) | MAOAALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11342686 | 0.71 | SMPD1 (0.32) | — | |
| SCHEMBL8920661 | 0.70 | FDPS (0.38) | CYP19A1MAOAMAOBSMN1; SMN2FDPS | |
| SCHEMBL6254433 | 0.69 | ABL1 (0.41) | ALDH1A1HTTKDM4EMEN1NPC1 | |
| SCHEMBL8922929 | 0.69 | APP (0.39) | CYP19A1APPNQO2MAOAMAOB | |
| SCHEMBL8922931 | 0.69 | APP (0.39) | CYP19A1APPNQO2MAOAMAOB | |
| SCHEMBL1629454 | 0.67 | ALOX5 (0.34) | ALDH1A1HTTKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |