Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065491 | 0.82 | HPGD (0.55) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL3310683 | 0.82 | LMNA (0.64) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL9016956 | 0.78 | LMNA (0.68) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL13378249 | 0.77 | LMNA (0.59) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL28206352 | 0.77 | CYP4A11 (0.60) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL15270528 | 0.77 | CYP4A11 (0.53) | HPGDLMNALOXL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL15393160 | 0.77 | LMNA (0.66) | HPGDLMNALOXL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16507466 | 0.76 | LMNA (0.57) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL15270773 | 0.76 | LMNA (0.57) | HPGDLMNALOXL2NPC1RAB9A | |
| SCHEMBL7249257 | 0.76 | LOXL2 (0.64) | HPGDLMNALOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |