SCHEMBL7984352

SCHEMBL7984352

Cc1ccc(S(=O)(=O)N[C@@](C)(Cc2ccc(C#N)cc2)C(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
ACHE P22303 1/20 0.47
CYP19A1 P11511 1/20 0.46
KMT2A Q03164 1/20 0.44
TAS2R14 Q9NYV8 1/20 0.44
GHSR Q92847 1/20 0.43
LSS P48449 1/20 0.42
RORC P51449 1/20 0.42
MMP13 P45452 3/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP3 P08254 2/20 0.41
MMP7 P09237 2/20 0.41
MMP9 P14780 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM1A O60341 1/20 0.41
ADAMTS4 O75173 1/20 0.41
EEF2K O00418 1/20 0.40
IDO1 P14902 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981743 0.90 MAPT (0.48) CYP19A1TAS2R14GHSRLSSMMP13
SCHEMBL7981747 0.90 MAPT (0.48) CYP19A1TAS2R14GHSRLSSMMP13
SCHEMBL6255018 0.85 GHSR (0.46) KMT2AGHSRMMP13MMP1MMP2
SCHEMBL6255022 0.85 GHSR (0.46) KMT2AGHSRMMP13MMP1MMP2
SCHEMBL7983911 0.83 KAT6A (0.49) KMT2ALSSL3MBTL1ALDH1A1
SCHEMBL7983907 0.83 KAT6A (0.49) KMT2ALSSL3MBTL1ALDH1A1
SCHEMBL7981503 0.79 EGFR (0.43) BCHEACHEKMT2AGHSRMMP13
SCHEMBL5996499 0.75 ALDH1A1 (0.48) KMT2AMMP13MMP1MMP2MMP9
SCHEMBL7984128 0.75 BLM (0.48) KMT2AGHSRTDP1ALDH1A1
SCHEMBL7984126 0.75 BLM (0.48) KMT2AGHSRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US disclosed
EP-1043309-A1 Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives LG Chemical Ltd. (KR) 2000-10-11 EP disclosed