Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.51 |
| ▸ | PIM1 | P11309 | 9/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625561 | 0.87 | PIM1 (0.49) | F2RL3PIM1FLT3PIM3PIM2 | |
| SCHEMBL624979 | 0.85 | ADORA2A (0.38) | F2RL3PIM1 | |
| SCHEMBL625541 | 0.84 | FYN (0.47) | F2RL3AURKA | |
| SCHEMBL623829 | 0.82 | F2RL3 (0.48) | F2RL3 | |
| SCHEMBL1945224 | 0.82 | F2RL3 (0.57) | F2RL3PIM1FLT3PIM2GSK3B | |
| SCHEMBL625548 | 0.82 | FYN (0.52) | PIM1FLT3PIM3PIM2KCNH2 | |
| SCHEMBL2257235 | 0.81 | F2RL3 (0.56) | F2RL3PIM1FLT3PIM3PIM2 | |
| SCHEMBL626108 | 0.81 | MAP3K12 (0.42) | — | |
| SCHEMBL623883 | 0.78 | F2RL3 (0.52) | F2RL3PIM1FLT3PIM2AURKA | |
| SCHEMBL624816 | 0.75 | PIM1 (0.51) | F2RL3PIM1FLT3PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |