SCHEMBL6256166

SCHEMBL6256166

COc1cccc(OC(N)C(C)O)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
MTNR1A P48039 10/20 0.49
MTNR1B P49286 10/20 0.49
PARP1 P09874 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
LMNA P02545 1/20 0.45
AOC3 Q16853 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL27864558 0.88 MRGPRX4 (0.52) MTNR1AMTNR1BPARP1CES2CES1
SCHEMBL11578736 0.81 TAAR1 (0.56) TAAR1MTNR1AMTNR1BPARP1CES2
SCHEMBL6262545 0.81 TAS1R3 (0.47) MTNR1AMTNR1BPARP1MAPK1ALDH1A1
SCHEMBL25179436 0.81 MTNR1B (0.54) MTNR1AMTNR1BPARP1TSHRMAPK1
SCHEMBL30333595 0.81 MTNR1B (0.54) MTNR1AMTNR1BPARP1TSHRMAPK1
SCHEMBL3826640 0.79 LMNA (0.45) MTNR1AMTNR1BALDH1A1LMNA
SCHEMBL11193473 0.78 KMT2A (0.49) PARP1L3MBTL1MAPK1CES2CES1
Hydrochloric Acid SCHEMBL5266256 0.77 ALDH1A1 (0.45) MTNR1AMTNR1BALDH1A1LMNA
SCHEMBL10885898 0.77 MGLL (0.47)
SCHEMBL178565 0.77 NPSR1 (0.57) TAAR1MTNR1AMTNR1BPARP1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005063699-A1 N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO disclosed