Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532120 | 0.91 | L3MBTL1 (0.49) | LTA4HTSHRNAAAGAAL3MBTL1 | |
| SCHEMBL20249535 | 0.90 | LTA4H (0.50) | LTA4HNAAAFFAR1SRD5A2GAA | |
| SCHEMBL11034783 | 0.85 | KDM4E (0.49) | LTA4HTSHRFFAR1 | |
| SCHEMBL30641469 | 0.82 | FFAR1 (0.47) | LTA4HTSHRFFAR1KMT2A | |
| SCHEMBL191669 | 0.82 | FFAR1 (0.47) | LTA4HTSHRFFAR1KMT2A | |
| SCHEMBL8597193 | 0.81 | AR (0.50) | — | |
| SCHEMBL8596617 | 0.81 | SMN1; SMN2 (0.56) | LTA4H | |
| SCHEMBL11036206 | 0.81 | SRD5A2 (0.41) | LTA4HNAAAFFAR1SRD5A2 | |
| 3-Methoxyphenylacetonitrile SCHEMBL7135147 | 0.80 | LTA4H (0.62) | LTA4HL3MBTL1 | |
| SCHEMBL8594741 | 0.80 | MAOB (0.59) | LTA4HFFAR1MAOAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174980-A1 | COMPOUND CONTAINING DIHYDROPHTHALAZINE AND ALKENYL AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2024-08-29 | — | — | WO | disclosed |
| CN-116577322-A | Visual nano detector and preparation method and application thereof | 北京化工大学 | 2023-08-11 | — | — | CN | disclosed |
| US-9156788-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2015-10-13 | — | — | US | disclosed |
| EP-2603490-A1 | NOVEL TRPV3 MODULATORS | AbbVie Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-06-13 | — | — | US | disclosed |
| CN-103140476-A | Novel trpv3 modulators | ABBOTT LAB | 2013-06-05 | — | — | CN | disclosed |
| WO-2012019315-A1 | NOVEL TRPV3 MODULATORS | ABBOTT LABORATORIES (US) | 2012-02-16 | — | — | WO | disclosed |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
| EP-1765796-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | Pfizer Products Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006003495-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| EP-0658542-B1 | PROCESS FOR PRODUCING ALPHA-HYDROXYIMINOPHENYLACETONITRILE | SHIONOGI & CO (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5629442-A | REACTION OF NITRILE WITH ALKYL NITRITE TO FORM OXIME SUBSTITUTED PHENYLACETONITRILE | SHIONOGI & CO., LTD. | 1997-05-13 | — | — | US | disclosed |
| WO-1997005132-A1 | AMINOACYL ADENYLATE MIMICS AS NOVEL ANTIMICROBIAL AND ANTIPARASITIC AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 1997-02-13 | — | — | WO | disclosed |
| EP-0658542-A1 | PROCESS FOR PRODUCING $g(a)-HYDROXYIMINOPHENYLACETONITRILE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4299839-A | Novel pesticides and pesticidal compositions cyclopropanecarboxylates and pesticidal method | KURARAY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-3984559-A | Compositions comprising tetramic acid analogs of pulvinic acid and methods of combating arthritis | SMITHKLINE CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |
| US-3947580-A | Anti-arthritic compositions comprising N-heterocyclic pulvinic acid amides and methods of producing anti-arthritic activity | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3931207-A | ANTIARTHRITIC | SMITHKLINE CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | TRPV3, TRPV4, TRPV5 | LTA4H 468/4885TSHR 1091/4885NAAA 4220/4885 |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PPARA, PPARG, PPARD | LTA4H 2962/4885TSHR 400/4885NAAA 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.