Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016275 | 0.80 | HTT (0.47) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL4959306 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL31461509 | 0.73 | FPR2 (0.51) | ALDH1A1LMNAHTTKDM5AKDM2B | |
| SCHEMBL27478632 | 0.73 | AGTR1 (0.38) | — | |
| Bromide SCHEMBL28340164 | 0.73 | AGTR1 (0.38) | ALDH1A1 | |
| SCHEMBL11686437 | 0.73 | FDPS (0.43) | ALDH1A1LMNAHSP90AA1HTTKDM5A | |
| SCHEMBL31461544 | 0.72 | FPR2 (0.44) | ALDH1A1HSP90AA1HSP90AB1HSP90B1MEN1 | |
| SCHEMBL7896604 | 0.71 | HSP90AA1 (0.45) | ALDH1A1LMNAHSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL28413796 | 0.71 | FPR2 (0.47) | ALDH1A1LMNAHSP90AA1MEN1KMT2A | |
| SCHEMBL27350357 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HSP90AA1KDM5AKDM2BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066188-A1 | A PROCESS FOR THE PREPARATION OF 2-(IMIDAZOL-1-YL)-1-HYDROXYETHANE-1, 1-DIPHOSPHONIC ACID | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2005-07-21 | — | — | WO | disclosed |