SCHEMBL6259252

SCHEMBL6259252

CC(C)(C)[Si]1(c2ccccc2)C(c2ccc([Si](C)(C)C)nc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccc([Si](C)(C)C)nc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6254908 0.83 HPGDS (0.39)
SCHEMBL6257861 0.83 NPC1 (0.35)
SCHEMBL6254507 0.83 PTGS2 (0.31) PTGS2
SCHEMBL6255405 0.82 PTGS2 (0.30) PTGS2
SCHEMBL6257555 0.81
SCHEMBL6256368 0.80 PTGS2 (0.33) PTGS2
SCHEMBL6255419 0.79 PDE4B (0.31) PTGS2
SCHEMBL8335527 0.77 KIF11 (0.41)
SCHEMBL6253656 0.77 CYP2A6 (0.31)
SCHEMBL6256045 0.76 NPC1 (0.31) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed