Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255997 | 0.85 | SMN1; SMN2 (0.32) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL6254507 | 0.84 | PTGS2 (0.31) | PTGS2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL6256045 | 0.83 | NPC1 (0.31) | PTGS2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL6255432 | 0.80 | NPC1 (0.40) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL6254179 | 0.80 | HPGDS (0.45) | — | |
| SCHEMBL6259252 | 0.80 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL10038535 | 0.78 | HPGDS (0.50) | NPC1RAB9ASMN1; SMN2ALOX15TSHR | |
| SCHEMBL7117261 | 0.77 | LIPG (0.31) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL7127205 | 0.76 | PTGS2 (0.33) | PTGS2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL10018832 | 0.74 | ALDH1A1 (0.43) | PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |