Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
| ▸ | ADH1C | P00326 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509817 | 0.87 | PIK3CD (0.31) | — | |
| SCHEMBL3225400 | 0.78 | LMNA (0.32) | LMNACES2CES1 | |
| SCHEMBL8944256 | 0.78 | ALDH1A1 (0.36) | ADH1AADH1CALDH1A1KDM4ENPC1 | |
| SCHEMBL3557381 | 0.76 | ALOX5 (0.42) | ADH1AADH1CALDH1A1CES2CES1 | |
| SCHEMBL1605450 | 0.76 | ALOX5 (0.42) | ADH1AADH1CALDH1A1CES2CES1 | |
| SCHEMBL1712105 | 0.75 | SPHK1 (0.47) | ADH1AADH1CLMNAALDH1A1KDM4E | |
| SCHEMBL13014531 | 0.75 | ADH1A (0.41) | ADH1AADH1CLMNAALDH1A1KDM4E | |
| SCHEMBL23158891 | 0.73 | ADH1A (0.39) | ADH1AADH1CLMNAALDH1A1KDM4E | |
| SCHEMBL1475937 | 0.73 | ALOX5 (0.40) | ADH1AADH1CCES2CES1FDPS | |
| SCHEMBL20350835 | 0.73 | ADH1A (0.39) | ADH1AADH1CLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009148004-A1 | NOVEL COMPOUND AND PHARMACEUTICAL APPLICATION OF SAME | 株式会社 三和化学研究所 (JP) | 2009-12-10 | — | — | WO | disclosed |
| WO-2005077319-A2 | HAIR TREATMENT COMPOSITIONS COMPRISING A PROTEIN DISULFIDE ISOMERASE | UNILEVER PLC (GB) | 2005-08-25 | — | — | WO | disclosed |