SCHEMBL8944256

SCHEMBL8944256

O=C(O)N(S)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ADH1A P07327 5/20 0.36
ADH1C P00326 3/20 0.35
ADH1B P00325 1/20 0.35
FDPS P14324 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MITF O75030 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
PAX8 Q06710 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ATM Q13315 1/20 0.34
PHGDH O43175 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6033756 0.87
SCHEMBL3557381 0.78 ALOX5 (0.42) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL1605450 0.78 ALOX5 (0.42) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL6259261 0.78 ADH1A (0.38) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL1475937 0.75 ALOX5 (0.40) CES2CES1ADH1AADH1CFDPS
SCHEMBL472875 0.74 CES2 (0.39) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL754311 0.74 PHGDH (0.46) ALDH1A1CES2CES1ADH1AADH1C
Hydrochloric Acid SCHEMBL5744499 0.72 PHGDH (0.44) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL3823899 0.72 CES2 (0.38) ALDH1A1CES2CES1ADH1AADH1C
SCHEMBL9538240 0.72 EPHX1 (0.50) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534486-A Herbicidal sulphonylaminocarbonyl triazolinones having substituents bonded via oxygen BAYER AKTIENGESELLSCHAFT (DE) 1996-07-09 US disclosed
US-5266555-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
US-5217522-A HERBICIDAL SULPHONYLGUANIDINOAZINES BAYER AKTIENGESELLSCHAFT (DE) 1993-06-08 US disclosed