Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18624724 | 0.76 | ADH1B (0.30) | — | |
| SCHEMBL12251524 | 0.74 | ADH1B (0.33) | — | |
| SCHEMBL24767641 | 0.73 | SHBG (0.35) | RENMETAP1 | |
| SCHEMBL23584192 | 0.72 | — | — | |
| SCHEMBL26144784 | 0.71 | ACHE (0.33) | — | |
| SCHEMBL24767638 | 0.71 | ADH1B (0.31) | — | |
| SCHEMBL6257233 | 0.68 | METAP1 (0.35) | METAP1 | |
| SCHEMBL26196153 | 0.67 | SHBG (0.37) | REN | |
| Isopropyl Alcohol SCHEMBL28449622 | 0.66 | CYP1A2 (0.42) | REN | |
| SCHEMBL12274452 | 0.66 | ACACB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |