Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12251524 | 0.98 | ADH1B (0.33) | ADH1BADH1CADH1AACHECYP1A2 | |
| SCHEMBL26144784 | 0.95 | ACHE (0.33) | ADH1BADH1CADH1AACHE | |
| SCHEMBL12274452 | 0.90 | ACACB (0.33) | — | |
| SCHEMBL23584192 | 0.82 | — | — | |
| SCHEMBL18642825 | 0.81 | — | — | |
| SCHEMBL24767638 | 0.80 | ADH1B (0.31) | ADH1BADH1CADH1AACHECYP1A2 | |
| SCHEMBL24767641 | 0.79 | SHBG (0.35) | ADH1BADH1CADH1AACHECYP1A2 | |
| SCHEMBL26196153 | 0.76 | SHBG (0.37) | ACHECYP1A2 | |
| SCHEMBL6259716 | 0.76 | REN (0.33) | — | |
| SCHEMBL23578957 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353610-A1 | SMALL MOLECULE MENIN INHIBITORS | SERVIER PHARMACEUTICALS LLC | 2021-11-18 | — | — | US | disclosed |
| US-20210198237-A1 | PIPERIDINES AS MENIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2021-07-01 | — | — | US | disclosed |
| US-20190152947-A1 | PIPERIDINES AS MENIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-23 | — | — | US | disclosed |
| US-10266521-B2 | Substituted heteroaryl compounds and methods of use | CALITOR SCIENCES, LLC (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180162841-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| US-20180162841-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| US-9938257-B2 | Substituted heteroaryl compounds and methods of use | CALITOR SCIENCES, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353610-A1 | SMALL MOLECULE MENIN INHIBITORS | MEN1, BRCA1, KRAS | ADH1B 2476/4885ADH1C 1774/4885ADH1A 1885/4885 |
| US-20210198237-A1 | PIPERIDINES AS MENIN INHIBITORS | MEN1, WFS1, BRCA1 | ADH1B 1159/4885ADH1C 571/4885ADH1A 367/4885 |
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | PRKACA, PRKDC, PRKACB | ADH1B 3651/4885ADH1C 3584/4885ADH1A 3785/4885 |
| US-20180162841-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | PRKACA, PRKDC, PRKACB | ADH1B 3651/4885ADH1C 3584/4885ADH1A 3785/4885 |
| US-20190152947-A1 | PIPERIDINES AS MENIN INHIBITORS | MEN1, GDI2, GNAQ | ADH1B 1070/4885ADH1C 706/4885ADH1A 401/4885 |
| US-10266521-B2 | Substituted heteroaryl compounds and methods of use | PRKACA, PRKDC, PRKACB | ADH1B 3651/4885ADH1C 3584/4885ADH1A 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.