Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | PGD | P52209 | 3/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260891 | 0.82 | LPAR5 (0.33) | METAP1PGK1PGK2LPAR5LPAR1 | |
| SCHEMBL6261707 | 0.81 | LPAR5 (0.33) | PGK1PGK2LPAR5LPAR1LPAR3 | |
| SCHEMBL6262026 | 0.76 | — | — | |
| SCHEMBL6257454 | 0.76 | MMP1 (0.33) | PGD | |
| SCHEMBL24767641 | 0.71 | SHBG (0.35) | METAP1 | |
| SCHEMBL6260667 | 0.70 | METAP1 (0.33) | METAP1 | |
| SCHEMBL18624724 | 0.69 | ADH1B (0.30) | — | |
| SCHEMBL6258650 | 0.69 | CA12 (0.32) | METAP1FBP1LPAR1LPAR3 | |
| SCHEMBL6257820 | 0.69 | CA12 (0.34) | LPAR1LPAR3 | |
| SCHEMBL6259716 | 0.68 | REN (0.33) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |