SCHEMBL625973

SCHEMBL625973

O=c1[nH]c(=S)ccn1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.94

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.94
P2RY6 Q15077 10/20 0.94
P2RY4 P51582 10/20 0.94
P2RY14 Q15391 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21418853 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
SCHEMBL21418854 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
SCHEMBL17972335 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
SCHEMBL14765539 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
Triphosphate SCHEMBL17894276 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
SCHEMBL3503025 1.00 P2RY2 (0.94) P2RY2P2RY6P2RY4P2RY14
SCHEMBL6319037 0.98 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
SCHEMBL2349022 0.98 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
SCHEMBL24371529 0.91 P2RY2 (0.79) P2RY2P2RY6P2RY4P2RY14
SCHEMBL21418912 0.91 P2RY2 (0.79) P2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 CN claimed
US-12460204-B2 Artificial nucleic acid molecules for improved protein or peptide expression CureVac SE (DE) 2025-11-04 US claimed
WO-2025105506-A1 NUCLEIC ACID, DRUG COMPOSITION, AND METHOD OF PRODUCING NUCLEIC ACID アンジェス株式会社 2025-05-22 WO claimed
US-20250136711-A1 SEMENOGELIN NEUTRALIZING ANTIBODY AND EPITOPE AND APPLICATION THEREOF SHANGHAI BIOTROY BIOTECHNIQUE CO., LTD (CN) 2025-05-01 US claimed
US-20240415958-A1 MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE TRANSLATE BIO INC (US) 2024-12-19 US claimed
CN-118924887-A HPV MRNA LNP vaccine 南京吉迈生物技术有限公司 2024-11-12 CN claimed
US-20240336901-A1 Modification of 3' Terminal Ends of Nucleic Acids by DNA Polymerase Theta UNIV TEMPLE (US) 2024-10-10 US claimed
US-20240327862-A1 Methods of Treating Rheumatoid Arthritis Using RNA-Guided Genome Editing of HLA Gene NATIONAL JEWISH HEALTH 2024-10-03 US claimed
US-20240309447-A1 METHODS AND KITS FOR PREPARING A SAMPLE COMPRISING ONE OR MORE RNA MOLECULES FOR SEQUENCING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-09-19 US claimed
EP-4400175-A2 METHODS OF TREATING RHEUMATOID ARTHRITIS USING RNA-GUIDED GENOME EDITING OF HLA GENE The Regents of the University of Colorado, a body corporate (US) 2024-07-17 EP claimed
US-20100189729-A1 RNA-CODED ANTIBODY CURVAC GMBH (DE) 2010-07-29 US claimed
US-20100047261-A1 BASE-MODIFIED RNA FOR INCREASING THE EXPRESSION OF A PROTEIN CUREVAC GMBH (DE) 2010-02-25 US claimed
WO-2009150156-A1 METHOD FOR ENZYMATIC SYNTHESIS OF CHEMICALLY MODIFIED RNA RIBOXX GMBH (DE) 2009-12-17 WO claimed
EP-2083851-A2 (BASE-)MODIFIED RNA FOR INCREASING THE EXPRESSION OF A PROTEIN Curevac GmbH (DE) 2009-08-05 EP claimed
WO-2008052770-A2 (BASE-)MODIFIED RNA FOR INCREASING THE EXPRESSION OF A PROTEIN CUREVAC GMBH (DE) 2008-05-08 WO claimed
US-20030039976-A1 Methods for base counting PE CORPORATION (NY) 2003-02-27 US claimed
JP-3331210-B2 2002-10-07 JP claimed
JP-2002508192-A 2002-03-19 JP claimed
EP-1038031-A1 MASS SPECTROMETRIC METHODS FOR SEQUENCING NUCLEIC ACIDS SEQUENOM, INC. (US) 2000-09-27 EP claimed
WO-1999031278-A1 MASS SPECTROMETRIC METHODS FOR SEQUENCING NUCLEIC ACIDS SEQUENOM, INC. (US) 1999-06-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12460204-B2 Artificial nucleic acid molecules for improved protein or peptide expression RNMT, NSUN3, RNGTT P2RY2 2992/4885P2RY6 2967/4885P2RY4 2730/4885
US-20100047261-A1 BASE-MODIFIED RNA FOR INCREASING THE EXPRESSION OF A PROTEIN RNMT, RNASE1, NSUN3 P2RY2 4516/4885P2RY6 4642/4885P2RY4 4740/4885
US-20240415958-A1 MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE NSUN3, RNMT, TRDMT1 P2RY2 3741/4885P2RY6 3298/4885P2RY4 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.